NL-OMON38828
Completed
Not Applicable
A study of biological, immunological and physiological parameters describing skin irritation induced by a physical stimulus in healthy male volunteers - Skin irritation induced by a physical stimulus
TNO0 sites30 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- skin irritation
- Sponsor
- TNO
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Healthy male subjects, 18 to 65 years of age, inclusive;
- •2\. Willing to undergo a shaving stimulus in the neck and upper leg;
- •3\. Fitzpatrick skin type I\-II\-III\-IV;
- •4\. Last shave 24\-36 hours prior to Day 1;
- •5\. Used to electrical shaving;
Exclusion Criteria
- •1\. External use of isotretinoin within 3 months prior to or during this study, or oral use of isotretinoin (Accutane® or Roaccutance®) within 6 months prior to or during this study;
- •2\. Coagulation problem or use of anticoagulation medicine, including the intensive use of Aspirin, where no wash\-out period of at least 1 week is taken into consideration;
- •3\. Use of corticosteroids within 2 weeks prior Day 1;
- •4\. Use of an antihistamine within 1 month prior to Day 1;
- •5\. Epilepsy, lupus erythematodes, \-porphyria;
- •6\. Collagen defect in the past, including keloid wound (keloid accumulation or keloid scar formation), history of bad wound healing;
- •7\. History with vascular diseases, like varicose veins in the area of treatment;
- •8\. History of immune disease (including HIV positively or AIDS), or an autoimmune disease, use of medicine for immune/autoimmune diseases;
- •9\. Treatment of any form of cancer (lately or in the past), history of skin cancer or other form of cancer in the area of treatment, present pre\-malignant lesions;
- •10\. Bad skin conditions on the area of treatment (like infections, open wound, scrape) or any other form of inflammation of the skin;
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Characterisation of COVID-19 long-term immunityCOVID-19 (SARS-CoV-2 infection)Infections and InfestationsISRCTN11946807niversity of Bristol372
Not yet recruiting
Not Applicable
Research for the Clinical Effect and Immune Mechanism of Soothing the Lung and Anti-fever, Resolving Blood-stasis and Unblocking Collaterals in the Treatment of Mycoplasma Pneumoniae Pneumonia in ChildreITMCTR1900002294First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Completed
Not Applicable
Clinical and immunological analysis on the effect of LEM in the adoptive immunotherapy using autologous activated lymphocytes in patients with incurable cancerIncurable cancerJPRN-UMIN000012283Kawasaki Medical School20
Recruiting
Not Applicable
Exploration of clinical and immunological/biomedical parameters of the post-COVID syndrome in the context of an outpatient rehabilitation conceptPost-COVID syndromeDRKS00025007niversitätsmedizin Greifswald180
Not yet recruiting
Not Applicable
Study of clinicopathological pattern in young breast cancerHealth Condition 1: C509- Malignant neoplasm of breast of unspecified siteCTRI/2022/08/044693O