Evaluating the pain relieving effects of Non-Thermal CO2 Laser Therapy (NTCLT) on chemotherapy induced oral mucositis

Phase 2

• Conditions: Chemotherapy-induced oral mucositis.; Oral mucositis (ulcerative) due to antineoplastic therapy; K12.31

• Registration Number: IRCT20220220054073N1
• Lead Sponsor: Iran National Science Foundation (INSF)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Chemotherapy-induced oral mucositis with grade 1-4 according to the WHO classification index
The minimum literacy to read and write and filling the forms
Providing written informed consent after the physician's explanation about the treatment method

Exclusion Criteria

Pregnancy
Breastfeeding
History of Photo sensitivity or use of photo sensitizing drugs
Head and neck radiotherapy
Taking narcotic painkillers

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
on-contact (Non-stimulate) pain score. Timepoint: before laser irradiation, immediately after laser irradiation, 4 hours, 8 hours after laser irradiation and then daily until the seventh day. Method of measurement: (Visual analogue scale) VAS.;Contact pain score. Timepoint: before laser irradiation, immediately after laser irradiation, 4 hours, 8 hours after laser irradiation and then daily until the seventh day. Method of measurement: (Visual analogue scale) VAS.