Routine Microcirculation Measurements in Intensive Care Unit Patients and Validation by PiCCO Technology. ROUMI-study

Recruiting

• Conditions: 10019280; Bloedsomloop; Circulation; organ perfusion

• Registration Number: NL-OMON49817
• Lead Sponsor: HagaZiekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

o Should be under PiCCO monitorization with routine clinic indication
o Should be older than 18 years
o Be suitable for monitoring in the intensive care unit
o Eligible for sublingual microcirculatory evaluation (not to have
maxillofacial injury, bleeding in the mouth)

Exclusion Criteria

o <18 years old
o Woman of childbearing potential with a positive pregnancy test
o Refusal to participate in the study or demand to end study for any reason
o Resistance during the measurements of sublingual microcirculation will lead
to end of the study.
o Moribund
o Intra-cardiac shunts, aortic aneurysm, aortic stenosis, mitral or tricuspid
insufficiency,
o Pneumonectomy, macro lung embolism

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>2.1 Primary Objectives:<br /><br>o To investigate the correlation of microcirculatory parameter MFI measured<br /><br>with Cytocam-IDF with Cardiac Index measured using the trans-pulmonary<br /><br>hemodilution technique PiCCO.<br /><br>o To assess the association between the microcirculatory parameters and<br /><br>macro-hemodynamic parameters during admission and interventions such as fluid<br /><br>resuscitation and vasopressor/inotrope/vasodilator administration.</p><br>