Comparison of Hemidiaphragmetic paralysis in supraclavicular vs Infraclavicular brachial plexus block in adult patients undergoing elective brachial vein transposition
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Assessment of Hemidiaphragmetic palsy in supraclavicular vs infraclavicular brachial plexus block
研究概览
简要总结
Following approval from the Institutional Ethical committee,
Patients will be evaluated for the eligibility of the study , and written informed consents will be obtained from enrolled participants by the study team before surgery .
A thorough pre anesthetic evaluation will be done 24 hrs prior to the procedure.
Patients will be randomly assigned using shuffled sealed ,opaque enveloped technique at
ratio of 1:1into two groups .
GROUP (SC)- Supraclavicular brachial plexus block
GROUP(CC)- Costoclavicular block
ANESTHETIC PROCEDURES
Patients in the age group of 20-60 of either sex undergoing elective basilic vein
transposition under brachial plexus block will be enrolled for the study with written
informed consent
On the day of surgery, a single anesthesiologist performs either the supraclavicular or
infraclavicular block. Prior to 30 minutes of surgery sonographic assessment of diaphragm
motion and contraction will be done using “ABCDE “ method described by Tsui et all(2).Which is performed by placing the probe at zone of apposition of anterior Axillary line,
watching for breathing (lung sliding), then moving caudally to identify the diaphragm for
evaluation . An 20 G iv cannula will be inserted and the patient is connected to standard
monitors such as noninvasive blood pressure , electrocardiography [ECG] and pulse
oximetry[Sp02].
All blocks will be performed under ultrasound guidance (Logiq p6 pro ultrasound system
manufactured by GE healthcare) by a single experienced Anesthesiologist using linear
probe of frequency 15-20 hz (11L) at different locations . Each patient will be
administered mixture of 22 ml, out of which 10 ml is 0.5% Bupivacaine , 10ml is 2%
lignocaine with adrenaline. , Dexamethasone 4mg (1ml) and clonidine 150mcg. .
Adequacy of sensory and motor blockade will be assessed .After about 30 minutes of
observation the movement of Diaphragm will be assessed using Ultrasonography by
using the ‘ABCDE teqnique. Patient satisfaction and complications like vascular puncture
and pneumothorax will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged 20 to 60 years undergoing elective basilic vein transposition under brachial plexus block.
排除标准
- •Patient refusal 2) Hypersensitivity to amide anesthetic 3) Pre-existing neuropathy to surgical limb 4) significant pulmonary disease 5)coagulopathy 6) infection at block site.
结局指标
主要结局
Assessment of Hemidiaphragmetic palsy in supraclavicular vs infraclavicular brachial plexus block
时间窗: From the time of brachial plexus block to 4 hours later
次要结局
- Adequacy of sensory, Motor blockade, Patient satisfaction, pulmonary complications(From the time of brachial plexus block to 4 hours later)