Comparison of Treatment of Recurrent HCC With Repeat Hepatectomy,and TACE With AFP Conversion
Not Applicable
Completed
- Conditions
- Recurrent Hepatocellular Carcinoma
- Interventions
- Procedure: TACEProcedure: Hepatectomy
- Registration Number
- NCT02728219
- Lead Sponsor
- Eastern Hepatobiliary Surgery Hospital
- Brief Summary
The purpose of this study is to compare the treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion.
- Detailed Description
Though many HCC patients have been benefited from hepatectomy treatment, still the high recurrence rate after the hepatectomy led to limited effectiveness.
This is the first study in same case system on comparison of effectiveness among repeat hepatectomy, and TACE with AFP conversion.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
- via clinical diagnosis and confirm it is early recurrent liver cancer with AFP conversion, and not accept any anticancer treatment.
- age:18-70years
- better liver function (Child-Pugh，class A or B)
Exclusion Criteria
- reject to attend；
- impossible to come to our hospital for physical examination regularly.
- cancer epitome、seed focus、lymph node or distant metastasis
- Blood clotting function hindrance;
- serious heart、lung、kidney disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description hepatectomy TACE Comparison of Treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion TACE Hepatectomy -
- Primary Outcome Measures
Name Time Method overall survival 3 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Eastern hepatobilliary surgery hospital
🇨🇳Shanghai, Shanghai, China