Evaluation of the effect of vaginal Progesterone in preventing preterm labor
Phase 3
- Conditions
- prevention of preterm labor.Preterm labour
- Registration Number
- IRCT138706051096N1
- Lead Sponsor
- Vice Chancellor for research-Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 260
Inclusion Criteria
Pregnant women were eligible to enter the trial if 1) they were between 26-36 weeks of gestation based on their LMP or sonography before 16 weeks of gestation. 2) Confirmation of premature delivery with a)uterine contractions more than 30 seconds and three or more contractions per 30 minutes established by tochodynamometer b) cervical dilatation of 0-2 cm in nulliparous and 1 -2 cm in multiparous and cervical effacement greater than 50% 3) intact membrane.
Exclusion criteria included: 1) unwillingness or inability to comply with study procedures before 36 weeks of gestation 2) lack of useful sufficient data 3) preeclampsia requiring termination of pregnancy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevention of preterm labour( before 37 weeks). Timepoint: 2 hours after insertion of suppository, then weekly visit. Method of measurement: control of uterine contraction.;Prevention of preterm labor (before 34 weeks). Timepoint: every two weeks. Method of measurement: Patient visits, uterine contraction determination.
- Secondary Outcome Measures
Name Time Method