Infection rate after cholecystectomy

Phase 3

• Conditions: Condition 1: symptomatic gallstones. Condition 2: polyps of gallbladder.; Cholelithiasis; Other diseases of gallbladder

• Registration Number: IRCT138805012220N1
• Lead Sponsor: Vice-Chancellor for Research,Shahid Beheshti University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

1-aged 20-80, 2- cholelithiasis with acute/chronic cholecystitis [based on three of the following signs; abdominal pain in the upper right quadrant, Murphy’s sign, leucocytosis > 10000/mm³, rectal temperature > 38 °C or < 36.5 °C plus, cholecystolithiasis (stones/sludge) or sonographic signs of cholecystitis (thickening and triple layer formation of the gall bladder wall) or polyps of gallbladder], 3- admitted in Shohada-e-Tajrish Hospital, Tehran, Iran for cholecystectomy between 2006 and 2008.
Exclusion criteria: 1- Pregnant women, 2-patients with jaundice at the time of diagnosis, 3- coagulopathy, 4-coledocholithiasis, 5- portal hypertension, 6- diabetes mellitus, 7- immunosuppressive disorders, 8-previous biliary surgery, 9- biliary pancreatitis, 10- history of antibiotic consumption within one week before surgery, 11-allergic reaction/anaphylaxis to penicillin or cephalosporins, 12- any acute emergency interventions, 13- any contraindications for LC (previous history of abdominal surgery), 14 -conversion from LC to OC, 15- do not agree with conditions of study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Complications of surgery method. Timepoint: during and one weak after surgery. Method of measurement: history and physical exam.;Spillage of bile/gallstone. Timepoint: during surgery. Method of measurement: observation.;Need for Subhepatic drain. Timepoint: within one weak after surgery. Method of measurement: cc of secretion.;Mean operation time. Timepoint: period between begining and end of surgery. Method of measurement: minute.;Bile culture results. Timepoint: one week after surgery. Method of measurement: culture results ,colony formation.;Surgical site infection. Timepoint: within one weak after surgery. Method of measurement: history,physical exam.;Hospital Stay. Timepoint: period between admition for surgery and discharge. Method of measurement: days.