Surgical-Site Infection After Laparoscopic Right Colectomy: A Cohort Study Comparing Intracorporeal Anastomosis in Front of Extracorporeal Anastomosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Anastomotic leak rate
研究概览
简要总结
Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay.
This study aimed to evaluate the postoperative surgical site infection (SSI) rate after laparoscopic right hemicolectomy with intracorporeal anastomosis, compared to extracorporeal anastomoses.
详细描述
This is a comparative cohort study of two anastomosis techniques for laparoscopic right hemicolectomy.
Between 2011 and 2019, all unselected consecutive patients who underwent a laparoscopic resection of the right colon were considered to be included in the study. The inclusion and exclusion criteria are detailed in the section below. Data were extracted from a prospectively maintained colorectal surgery database of a university-affiliated hospital in Barcelona.
All included patients signed a standard consent form after being informed about the characteristics of the procedure. Institutional board approval was obtained before the review of the patients' data.
Patients were divided into two groups, depending on the anastomotic technique performed: intracorporeal (IA) or extracorporeal.
The primary endpoint of the study was to determine the surgical-site infection (SSI) rate and its potential impact on the length of hospital stay. Anastomotic leak was defined as a "leak of luminal contents from a surgical join between two hollow viscera" according to the Surgical Infection Study Group [1]. The evaluation of SSI, intraabdominal abscess and wound infection (both superficial and deep), was based on the Centers for Disease and Prevention definitions [2].
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients over 18 years candidates for scheduled surgery with curative intention to resect a benign or malignant neoplasm of the right colon
排除标准
- •stage IV disease (distant metastatic or intraabdominal disseminated disease that contraindicates surgery with curative intention)
- •emergency operation for complicated disease
- •medical contraindication for general anesthesia
- •pregnancy
- •chronic renal insufficiency requiring dialysis
- •or patient refusal and/or absence of informed consent.
结局指标
主要结局
Anastomotic leak rate
时间窗: 30 days
percentage of clinical anastomotic leak leading to an intervention
Wound Infection
时间窗: 30 days
percentage of wound infection (deep or superficial)
Intraabdominal Abscess rate
时间窗: 30 days
percentage of abdominal abscess (clinical or radiological) leading to an intervention (surgical or percutaneous)
次要结局
- postoperative complications 2(30 days)
- postoperative complications 1(30 days)
- Length of Hospital Stay(30 days)
- Operating time of the procedure(During the perioperative period)