Efficacy of non-invasive ventilation versus standard oxygen therapy in emergency patients with respiratory distress: A randomized controlled trial
Phase 4
Completed
- Conditions
- respiratory distress,emergency departmentrespiratory distressnon-invasive ventilationrespiratory rate
- Registration Number
- TCTR20150325002
- Lead Sponsor
- Faculty of medicine, Siriraj Hospital, Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
age more than 18 years
respiratory rate more than 24 breath per minuts
use of accessory muscle or abdominal paradox
room air oxygen saturation below 95 %
Exclusion Criteria
Cardiac arrest
Unstable medical condition e.g. shock myocardial infarction
Respiratory failure defined by respiratory rate > 35 breath per minutes and oxygen saturation < 90% after oxygen theary
High risk for aspiration
Large amount of secretion
Glasgow coma scale < 13
unco-operated patients
untreated pneumothorax
recent airway or upper GI tract or esophageal surgery
unfit mask
pregnancy
required immediate intubation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method respiratory rate 120 minutes breaths per minute
- Secondary Outcome Measures
Name Time Method respiratory rate 60 minutes breaths per minute,pulse rate 120 minutes beats per minute,intubation rate within 24 hours percentage,mortality rate within 7 days percentage,hospital length of stay no days,complication of non-invasive ventilation no percentage,success rate of non-invasive ventilation no percentage