The role of NIV in COVID 19 patinets
Phase 2
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: J00-J99- Diseases of the respiratory system
- Registration Number
- CTRI/2021/06/033979
- Lead Sponsor
- Government medical College Baroda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age more than 18 years
2. Both Gender
3. Following Symptoms and signs:
a) breathlessness at rest;
b) RR > 30 /min, use of accessory respiratory muscles, paradoxical
breathing.
c) SpO2 <90%
4. ABG Analysis : a) pH < 7.35; PaO2 <80mm Hg PaCO2 > 45 mm Hg. Art.,
b) PaO2/FiO2 <300
Exclusion Criteria
1. Signs of altered consciousness
2. Unstable hemodynamics
3. Inability to protect the respiratory tract. (absence/diminished
protective airway reflexes)
4. Excessive bronchial secretion.
5. Uncooperative patients.
6.Facial trauma, burns, anatomical disorders that prevent masking
7.Patients with uncontrolled DM and/or HT
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the outcome after using NIV in COVID 19 patients <br/ ><br>Timepoint: 6 months
- Secondary Outcome Measures
Name Time Method 1. (a)To observe ventilatory parameters like FiO2 <br/ ><br>requirement ,IPAP , EPAP support and expiratory tidal volume <br/ ><br>for maintaining target SPO2 90%.and (b) ABG changes ( pH, PaO2,PaCO2,P/F ratio) <br/ ><br>2. To observe hemodynamic parameters and SpO2 of the patient <br/ ><br>with use of NIV. <br/ ><br>3. The outcome and success rate of NIV in COVID 19 <br/ ><br>4.To observe Complications associated with NIV if any.Timepoint: 6 months