MedPath

Effect of Celecoxib on Transitional Pain After Outpatient Surgery

Phase 4
Withdrawn
Conditions
Pain
Interventions
Drug: placebo
Registration Number
NCT00664690
Lead Sponsor
Lawson Health Research Institute
Brief Summary

Sixty adults having shoulder and forearm surgery will receive either placebo or celebrex started preoperatively and continued for 3 days. Rescue medications required as well as pain scores will be assessed using a patient diary to evaluate the effect of celebrex in controlling transitional pain

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Patients scheduled for elective ambulatory surgery of the shoulder
  • ASA I - III
  • Able to read English
  • Male or female
Exclusion Criteria
  • Allergy to local anesthetic, Cox2, sulpha drug, acetaminophen or oxycodone
  • Women who are pregnant or lactating and women of childbearing age and not following acceptable contraceptive precautions
  • Any major medical or psychiatric problem
  • Those with a known history of narcotic dependence, abuse or chronic narcotic intake
  • Patients with known history of peptic ulcer or GI bleeding in the past, ulcers, congestive heart failure, angina or previous heart attack, coagulation problems, venous thrombosis, kidney or liver disease or strokes

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
2placeboplacebo
1celebrexcelebrex
Primary Outcome Measures
NameTimeMethod
visual analogue score for painpost-op period
Secondary Outcome Measures
NameTimeMethod
severity of nauseapost-op period

Trial Locations

Locations (1)

St. Joseph's Health Care

🇨🇦

London, Ontario, Canada

© Copyright 2025. All Rights Reserved by MedPath