Microcirculatory Assessment in Patients With Trauma and Severe Burns
Not Applicable
Withdrawn
- Conditions
- BurnsTrauma
- Interventions
- Other: micro-imaging
- Registration Number
- NCT01922960
- Lead Sponsor
- University of South Alabama
- Brief Summary
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Detailed Description
Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock).
The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients with severe burns/trauma ages 19-80. Patients undergoing elective abdominal or cardiothoracic surgery ages 19-69 years old
Exclusion Criteria
- Patients undergoing elective surgery < 19 years old.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description micro-imaging micro-imaging Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints. Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 \& Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,\& closing of surgical wound.
- Primary Outcome Measures
Name Time Method dysfunctional capillary density correlates with development of multiple organ failure approximately 1 year to assess outcome measure
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of South Alabama Medical Center
🇺🇸Mobile, Alabama, United States