Microcirculatory Assessment in Patients With Trauma and Severe Burns
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- dysfunctional capillary density correlates with development of multiple organ failure
研究概览
简要总结
Predict the development of multiple organ failure in patients with trauma and severe burns.
详细描述
Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock).
The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with severe burns/trauma ages 19-
- •Patients undergoing elective abdominal or cardiothoracic surgery ages 19-69 years old
排除标准
- •Patients undergoing elective surgery < 19 years old.
研究组 & 干预措施
micro-imaging
Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints.
Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 & Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,& closing of surgical wound.
干预措施: micro-imaging (Other)
结局指标
主要结局
dysfunctional capillary density correlates with development of multiple organ failure
时间窗: approximately 1 year to assess outcome measure
次要结局
未报告次要终点
研究者
William Richards
Study Chair and Principle Investigator
University of South Alabama