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Clinical Trials/NCT05227586
NCT05227586
Completed
Not Applicable

Adjunctive Right Atrial Ablation for Persistent Atrial Fibrillation With Right Atrial Enlargement

Shanghai Chest Hospital1 site in 1 country195 target enrollmentNovember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Persistent Atrial Fibrillation
Sponsor
Shanghai Chest Hospital
Enrollment
195
Locations
1
Primary Endpoint
atrial fibrillation (AF) recurrence rate
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This is retrospective cohort study testing whether patients with persistent atrial fibrillation and right atrial enlargement may benefit from adjunctive right atrial ablation.

Detailed Description

This is retrospective cohort study testing whether patients with persistent atrial fibrillation and right atrial enlargement may benefit from adjunctive RA ablation. We enrolled 65 patients with persistent atrial fibrillation and right atrial enlargement received adjunctive right atrial ablation. These patients were 1:2 match with 130 patients received left atrial ablation only. Atrial fibrillation recurrence rate and other paremeters were analyzed to evaluate the efficacy of adjunctive right atrial ablation in this subset of patients.

Registry
clinicaltrials.gov
Start Date
November 1, 2021
End Date
January 20, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Xu Liu

Professor, deputy director of cardiology department of Shanghai Chest Hospita

Shanghai Chest Hospital

Eligibility Criteria

Inclusion Criteria

  • Aged 18 to 80 years old;
  • Persistent AF with right atrial enlargement;
  • Nonresponse or intolerance to ≥1 antiarrhythmic drug.

Exclusion Criteria

  • History of catheter ablation;
  • valvular heart disease;
  • hypertrophic cardiomyopathy or dilated cardiomyopathy;
  • Without follow-up data

Outcomes

Primary Outcomes

atrial fibrillation (AF) recurrence rate

Time Frame: at 12 months post procedure

AF recurrence is defined as presence of documented AF episodes of 30 seconds or longer duration

Secondary Outcomes

  • atrial fibrillation (AF)/atrial flutter (AFL)/atrial tachycardia (AT) recurrence rate(at 12 months post procedure)

Study Sites (1)

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