EUCTR2008-006846-24-GB
Active, not recruiting
Phase 1
An Evaluation of the Effectiveness of Ibuprofen and Morphine for Acute Pain in Sickle Cell Disease - Ibuprofen and Morphine for Acute Sickle Cell Pain
orth West London Hospitals NHS Trust0 sites320 target enrollmentDecember 12, 2008
ConditionsSickle Cell Disease
DrugsNurofen Caplets
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Sickle Cell Disease
- Sponsor
- orth West London Hospitals NHS Trust
- Enrollment
- 320
- Status
- Active, not recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult patients with SCD of any phenotype and gender aged 16 years and over
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •1\. Patient has a history of allergic reaction to either morphine or ibuprofen
- •2\. Patient has contraindications to morphine or ibuprofen, e.g. peptic ulcer disease, NSAID\-induced asthma
- •3\. Patient in a drug dependency programme
- •4\. Patient is on renal dialysis
- •5\. Stroke within the last 6 weeks
- •6\. Platelet count \< 50 X 10E9/l
- •7\. Patient is pregnant or breastfeeding
- •8\. Doctor unwilling to randomise the patient for other reasons
- •9\. Previous participation in the trial
Outcomes
Primary Outcomes
Not specified
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