ISRCTN97241637
Completed
未知
An evaluation of the effectiveness of ibuprofen and morphine for acute pain in sickle cell disease: a double-blind, placebo-controlled randomised trial
orth West London Hospitals NHS Trust (UK)0 sites320 target enrollmentApril 8, 2009
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Sickle cell disease
- Sponsor
- orth West London Hospitals NHS Trust (UK)
- Enrollment
- 320
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult patients with SCD of any phenotype and gender aged 16 years and over.
Exclusion Criteria
- •1\. Patient has a history of allergic reaction to either morphine or ibuprofen
- •2\. Patient has contraindications to morphine or ibuprofen, e.g. peptic ulcer disease, non\-steroidal anti\-inflammatory drug (NSAID)\-induced asthma
- •3\. Patient in a drug dependency programme
- •4\. Patient is on renal dialysis
- •5\. Stroke within the last 6 weeks
- •6\. Platelet count less than 50 x 10^9/l
- •7\. Patient is pregnant or breastfeeding
- •8\. Doctor unwilling to randomise the patient for other reasons
- •9\. Previous participation in the trial
Outcomes
Primary Outcomes
Not specified
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