COMPARING THE EFFICACY OF RIBOFLAVIN A PHOTOSENSITISING COMPOUND AND CHLORHEXIDINE VARNISH IN CONTROLLING ORAL MICROFLORA IN ORTHODONTIC PATIENTS A RANDOMISED CONTROLLED TRIAL
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Comparing the reduction of bacterial count among the experimental groups.
研究概览
简要总结
This study is a Randomised, parallel, active controlled trial which compares the efficacy of 0.5% riboflavin in solution form and 0.12% chlorhexidine mouthwash given once a week for consecutively four weeks in 30 orthodontic patients who are undergoing treatment for the past 6 months. The primary outcome of the study will be comparing the reduction of bacterial count at T0 ( before application), T1 (Immediately after application, T2 ( 60 days from initial application). The secondary outcomes will be assessing the viability of bacterias using confocal laser scanning microscopy at T0 and T1.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Good general health Absence of systemic antibiotic intake at least 3 months prior to study, Under fixed orthodontic treatment Absence of oral lesions Supragingival calculus Severe malocclusion Evident dental plaque accumulation.
排除标准
- •The use of mouthwashes during the study and the follow-up, Pregnancy Systemic disorders History of parafunctional and deleterious habits (tobacco chewing).
结局指标
主要结局
Comparing the reduction of bacterial count among the experimental groups.
时间窗: T0 - Before application of test agents | T1- Immediately after application | T2 - 60 days after application
To find out the number of live and dead bacterias using confocal laser microscopy
时间窗: T0 - Before application of test agents | T1- Immediately after application | T2 - 60 days after application
次要结局
- To assess the percentage of live and dead bacterias using confocal laser scanning microscopy(T0,T1)
研究者
SobikaS
Sri venkateswara dental college and hospital