Optimising mealtime insulin bolusing algorithms for dietary fat to improve glycaemic control in adults with type 1 diabetes.

Not Applicable

Completed

• Conditions: Type 1 Diabetes; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12617000828325
• Lead Sponsor: The University of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-06-06
• Last Update Posted: 3 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Aged 18-70y, T1D diagnosed for less than or equal to 1 year, CSII for less than or equal to 3 months, HbA1c for less than or equal to 8.5% (69 mmol/mol), reliably performing self-monitoring of blood glucose at least four times daily and fluency in English.

Exclusion Criteria

Concurrent medical issues including coeliac disease and gastroparesis, food allergies, intolerances or eating disorders or use of other medication that may influence blood glucose levels, pregnancy or lactation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences in 5hr iAUCglucose (Part 1)[The 5hr iAUCglucose will be calculated from capillary blood glucose level measurements taken at 15-30 minute intervals for 5 hrs (0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240, 270, 300 minutes).];Mean insulin dose (Part 2)[Insulin dose administered for the study session is recorded at the time the insulin dose is given (t = 0)];Mean insulin dose dual-wave split (Part 2)[Insulin dose dual-wave split administered for the study session is recorded at the time the insulin dose is given (t = 0)]