Aerobic Exercise and Oxygen Uptake Efficiency Slope in Coronary Artery Disease

Phase 2

Completed

• Conditions: Coronary Artery Disease
• Interventions: Other: Aerobic exercise training

• Registration Number: NCT02394236
• Lead Sponsor: Hospital TotalCor

Brief Summary

Thus, the purpose of the present study was to evaluate the effects of continuos exercise training (CET) and interval exercise trainining (IET) on oxygen uptake efficiency slope (OUES) in patients with coronary artery disease.

Detailed Description

The oxygen uptake efficiency slope (OUES) is a submaximal index that incorporates cardiovascular, peripheral and pulmonary factors that determine ventilatory response to exercise. There is scarce information about the effects of the mode and intensity of exercise training on OUES in patients with coronary artery disease.

Study Timeline

• Study Start: 2012-09
• Primary Completion: 2013-10
• Study Completion: 2014-11
• Status Verified: 2015-03
• Study First Submitted: 2015-03-16
• Study First Submitted QC: 2015-03-19
• Last Update Submitted: 2015-03-19
• Study First Posted: 2015-03-20
• Last Update Posted: 2015-03-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• stable coronary artery disease diagnosed by coronary angiography

Exclusion Criteria

• unstable angina pectoris,
• complex ventricular arrhythmias,
• pulmonary congestion and
• orthopaedic or neurological limitations to exercise

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Continuous exercise training	Aerobic exercise training	The continuous exercise training was performed on a treadmill with a 50-minutes duration and intensity at ventilatory anaerobic threshold.
interval exercise training	Aerobic exercise training	The interval exercise training consisted of 7 sets of 3 minutes at respiratory compensation point and 7 sets of 3 minutes of exercise at moderate intensity corresponding to the ventilatory anaerobic threshold totaling 42 minutes

Primary Outcome Measures

Name	Time	Method
The oxygen uptake efficiency slope	up to 3 months	The oxygen uptake efficiency slope (OUES) is a submaximal index that incorporates cardiovascular, peripheral and pulmonary factors that determine ventilatory response to exercise.