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The effect of finasteride and hydroxy chloroquine on frontal fibrosing alopecia

Phase 2
Recruiting
Conditions
Frontal fibrosing alopecia.
Cicatricial alopecia, unspecified
L66.9
Registration Number
IRCT20210513051276N1
Lead Sponsor
Esfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

New cases with FFA who have not yet received any medication.
Patients who have previously received systemic therapy and have not received systemic medication for at least the last three months and according to clinical and dermoscopic criteria, their disease is active.
Patients treated with topical medication and according to clinical and dermoscopic criteria, their disease is active

Exclusion Criteria

Pregnancy or lactation
History of hypersensivity due to hydroxychloroquine or finasteride
Patients with severe blood dyscrasia and liver dysfunction
Patients with retinopathy
Personal history or family history of breast cancer

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Frontal fibrosing alopecia severity index. Timepoint: Before and after intervention. Method of measurement: Checklist.;Standardized global photography. Timepoint: Before and after intervention. Method of measurement: Based on scoring by two dermatologist.;Tricoscopy. Timepoint: Before and after intervention. Method of measurement: Based on scoring by two dermatologist.
Secondary Outcome Measures
NameTimeMethod
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