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Clinical Trials/NCT05382026
NCT05382026CompletedNot Applicable

Milk Versus a Pea-based Beverage for Increasing Muscle Mass and Bone Mineral Density During Resistance Training in Adolescent Boys and Girls

University of Saskatchewan1 site in 1 country112 target enrollmentStarted: May 24, 2022Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
112
Locations
1
Primary Endpoint
Change in lean tissue mass (kg)

Study Overview

Brief Summary

Canada's Food Guide places an increased emphasis on plant-based proteins; however, Canadians who consume a plant-based diet may be compromised because of intake of lower-quality protein. Consumption of high-quality protein is important during growth and development, especially in highly active individuals. The study will compare milk (i.e. high quality protein) to a pea-based beverage (i.e. lower quality plant-based protein) in adolescent boys and girls who are engaged in resistance-training programs as part of their athletic training. One-hundred and fourteen adolescent boys and girls (12-17y of age) will be divided into groups that consume milk, a pea-beverage, or a carbohydrate (sugar) beverage after resistance training sessions performed three times per week for six months. It is predicted that the group consuming milk will have greater increases in muscle mass, strength, and bone density, and greater reductions in fat mass compared to the groups consuming a pea-based or carbohydrate beverages.

Detailed Description

Milk protein is important especially for very active people and in the context of plant-based diets, which are lower in protein quality. The purpose of the study is to compare the effectiveness of milk supplementation to pea-beverage supplementation during resistance training programs for increasing lean tissue mass in adolescent boys and girls. Secondary and tertiary outcomes include fat mass, bone mineral density, and muscular strength. It is hypothesized that milk supplementation during resistance training will be more effective than plant-based proteins (i.e. pea-beverage) for increasing muscle mass, reducing fat mass, and improving bone mineral outcomes in adolescent boys and girls. One-hundred and fourteen boys and girls (aged 12-17y) who are currently enrolled in resistance training programs (3 times per week for 6 months) as part of their competitive athletic programs will be stratified by sex and maturity status before being randomized to three groups: 1) 1% chocolate milk supplementation; 2) pea-based beverage; 3) carbohydrate beverage (placebo control). Beverages will be consumed during recovery from each resistance training session (i.e. 250 ml immediately after training and 250 ml one hour later to optimize post-exercise protein synthesis) over the six-month intervention. It is anticipated that milk supplementation will be more effective than plant-based protein supplementation.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Other
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
12 Years to 17 Years (Child)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Currently participating in a resistance-training program 3 times per week
  • •Female participants must have reached menarche

Exclusion Criteria

  • •Have taken any nutritional supplement (e.g., protein, creatine, amino acids) within the past month
  • •Currently taking anabolic steroids or oral corticosteroids
  • •Allergies to dairy, almonds, cashews, or peas

Arms & Interventions

1% chocolate milk

Experimental

250 ml of 1% chocolate milk consumed immediately after resistance training sessions + 250 ml of chocolate milk consumed 1 hour after resistance training sessions

Intervention: Nutritional supplementation during a 6 month resistance training program (Dietary Supplement)

Pea-based beverage

Active Comparator

250 ml of pea beverage consumed immediately after resistance training sessions + 250 ml of pea beverage consumed 1 hour after resistance training sessions

Intervention: Nutritional supplementation during a 6 month resistance training program (Dietary Supplement)

Placebo: Low protein plant-based beverage

Placebo Comparator

250 ml of placebo beverage consumed immediately after resistance training sessions + 250 ml of placebo beverage consumed 1 hour after resistance training sessions

Intervention: Nutritional supplementation during a 6 month resistance training program (Dietary Supplement)

Outcomes

Primary Outcomes

Change in lean tissue mass (kg)

Time Frame: 6 months

Lean tissue mass measured by dual energy X-ray absorptiometry

Secondary Outcomes

  • Change in cortical thickness at the hip (cm)(6 months)
  • Change in fat mass (kg)(6 months)
  • Change in bench press strength (kg)(6 months)
  • Change in squat strength (kg)(6 months)
  • Change in lumbar spine bone mineral density (g/cm-squared)(6 months)
  • Change in hip bone mineral density (g/cm-squared)(6 months)
  • Change in cross-sectional area at the hip (cm-squared)(6 months)
  • Change in cross-sectional moment of inertia at the hip (cm to the power of 4)(6 months)
  • Change in buckling ratio at the hip (no units)(6 months)
  • Change in section modulus at the hip (cm to the power of 3)(6 months)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Phil Chilibeck

Professor

University of Saskatchewan

Study Sites (1)

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