Transcranial Direct Current Stimulation (tDCS) as a Cognitive Functioning Enhancement Treatment for ADHD Patients Compared to Healthy Controls
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Transcranial Direct Current Stimulation
- Sponsor
- Hebrew University of Jerusalem
- Enrollment
- 63
- Locations
- 1
- Primary Endpoint
- Navon task
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This study will examine the possible effects of tDCS (Transcranial Direct Current Stimulation) treatment to the left DLPFC on cognitive functions which were found to be deficient amongst ADHD patients. The study will include 100 subjects, 50 of whom diagnosed with ADHD. Subjects will complete the ASRS questionnaire to measure ADHD symptoms severity. Next, subjects will complete a series of cognitive tasks, after which they will receive either tDCS treatment or a sham treatment. Finally, subjects will repeat the cognitive tasks. Later that day, a telephonic follow up will take place. ADHD symptoms will be assessed again the next day.
Investigators
Noa Beiman
Principal Investigator
Hebrew University of Jerusalem
Eligibility Criteria
Inclusion Criteria
- •Participation criteria for healthy participants
- •Right hand dominance.
- •No psychiatric nor neural diagnosis.
- •Participants must be able to comprehend the study's procedure and sign an informed consent.
- •Participation criteria for ADHD diagnosed participants
- •ADHD diagnosis (according to DSM V).
- •Right hand dominance.
- •Participants must be able to comprehend the study's procedure and sign an informed consent.
- •Participants who regularly use Methylphenidate will be required to avoid the medication for 24 hours prior to study and 12 hours post study.
Exclusion Criteria
- •a. Other psychiatric diagnoses (additional to ADHD). b. Drug use (excluding Methylphenidate). c. Neurological disorders. d. Pacemaker, Insulin pump
Outcomes
Primary Outcomes
Navon task
Time Frame: through study completion, up to 1 hour after treatment
change in accuracy, shorter RT's
Stop-signal
Time Frame: through study completion, up to 1 hour after treatment
change in response inhibition: shorter SSRT
N-back
Time Frame: through study completion
change in working memory: increase in hit rate
Stroop
Time Frame: through study completion, up to 1 hour after treatment
change in interference control: smaller interference effect
Time Reproduction task
Time Frame: through study completion, up to 1 hour after treatment
change in time perception: increased accuracy
Continuous Performance Task
Time Frame: through study completion, up to 1 hour after treatment
change in continuous concentration: increase in accuracy