Gastric acid secretion study in Japanese (both elderly and non-elderly subjects)
Not Applicable
- Conditions
- gastroesophageal reflux disease:GERD
- Registration Number
- JPRN-UMIN000008906
- Lead Sponsor
- Research Organization for GastroEnterological disease Treatment (ROGET)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Not provided
Exclusion Criteria
Peptic ulcer History of gastrointestinal surgery (except for surgery for appendicitis and hemorrhoid) History of malignant tumor, renal failure, and other gastrointestinal diseases that may affect the study The use of drugs, including over-the-counter (OTC) drugs that affect gastric acid secretion (except for the as-needed use of drugs that can be discontinued from 2 weeks before gastric acid collection) History of H. pylori eradication The use of antithrombogenic drug The volunteer who is otherwise ineligible for the study in the investigator's opinion
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure the basal acid output (BAO) and maximal acid output (MAO) separately in elderly (age 65 or over) and non-elderly subjects in each of the H. pylori-negative and H. pylori-positive groups.
- Secondary Outcome Measures
Name Time Method he following parameters will be measured and analyzed: Serum pepsinogen I and II levels Fasting serum gastrin levels Correlation between the fasting serum gastrin and the BAO/MAO Correlation between the serum pepsinogen and the BAO/MAO Gastric acid secretion in young subject (H. pylori-negative) Others