NL-OMON20697招募中不适用
The value of nerve ultrasound in patients with neurofibromatosis type 1
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- Erasmus MC
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •Age =18 years
- •-Diagnosed with NF1 (see below for diagnostic criteria)
- •-Treatment at the outpatient clinic of the Erasmus MC Cancer Institute (Rotterdam)
- •Criteria for diagnosis NF1:
- •Two or more of the following clinical features are sufficient to establish a diagnosis of neu-rofibromatosis type 1:
- •Six or more cafe-au-lait macules (>0,5 cm at largest diameter in a prepubertal child or >1,5 cm in post-pubertal individuals)
- •Axillary freckling or freckling in inguinal regions
- •Two or more neurofibromas of any type or one or more plexiform neurofibromas
- •Two or more Lisch nodules (iris hamartomas)
- •A distinctive osseous lesion (sphenoid wing dysplasia, long-bone dysplasia)
- •An optic pathway glioma
- •A first-degree relative with neurofibromatosis type 1 diagnosed by the above criteria
排除标准
- •-comorbidity associated with (poly)neuropathy (e.g. alcoholism, diabetes mellitus)
- •-comorbidity mimicking neuropathic complaints (e.g. myelopathy)
- •-inability to give informed consent or to undergo HRUS
研究者
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