NL-OMON20697
Recruiting
Not Applicable
The value of nerve ultrasound in patients with neurofibromatosis type 1
Conditionseurofibromotosis type 1
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- eurofibromotosis type 1
- Sponsor
- Erasmus MC
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \=18 years
- •\-Diagnosed with NF1 (see below for diagnostic criteria)
- •\-Treatment at the outpatient clinic of the Erasmus MC Cancer Institute (Rotterdam)
- •Criteria for diagnosis NF1:
- •Two or more of the following clinical features are sufficient to establish a diagnosis of neu\-rofibromatosis type 1:
- •Six or more cafe\-au\-lait macules (\>0,5 cm at largest diameter in a prepubertal child or \>1,5 cm in post\-pubertal individuals)
- •Axillary freckling or freckling in inguinal regions
- •Two or more neurofibromas of any type or one or more plexiform neurofibromas
- •Two or more Lisch nodules (iris hamartomas)
- •A distinctive osseous lesion (sphenoid wing dysplasia, long\-bone dysplasia)
Exclusion Criteria
- •\-comorbidity associated with (poly)neuropathy (e.g. alcoholism, diabetes mellitus)
- •\-comorbidity mimicking neuropathic complaints (e.g. myelopathy)
- •\-inability to give informed consent or to undergo HRUS
Outcomes
Primary Outcomes
Not specified
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