Sepsis Epidemiology in Paediatric Acute Care International (SENTINEL International) Study

Not Applicable

• Conditions: sepsis; Emergency medicine - Other emergency care; Infection - Other infectious diseases; Inflammatory and Immune System - Other inflammatory or immune system disorders; Public Health - Epidemiology

• Registration Number: ACTRN12624000052538
• Lead Sponsor: Murdoch Children's Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-01-23
• Last Update Posted: 29 January 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 3500

Inclusion Criteria

Age less than 18 years AND
Admission to hospital AND
Treatment with intravenous (IV)/ intramuscular (IM)/ intraosseous (IO) antibiotics pre-hospital or in ED AND
Circulatory support (fluid bolus or inotropic support) pre-hospital or in ED OR
Admission diagnosis of suspected sepsis, septicaemia or septic shock

Fluid bolus defined as equal to or greater than 5ml/kg or 500mls administered over less than 30 minutes to treat impaired perfusion (not dehydration)
Inotropic support defined as intravenous infusion of inotrope/vasopressor

Exclusion Criteria

Patients not initially seen in the Emergency Department (i.e. transferred directly to the ward including ICU)
Patients presenting with trauma
Patients transferred from another hospital if > 24 hours since presentation

Study & Design

• Study Type: Observational
• Study Design: Not specified