Comparative evaluation of different oxygen flow rates through nasal cannula on the efficacy of preoxygenation
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Maulana Azad Medical College
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- End tidal oxygen concentration after 3 mins of preoxygenation in well-sealed face mask and in a combination of both face mask and nasal cannula (at flow rates of 0L/min, 5L/min and 10L/min
Study Overview
Brief Summary
Preoxygenation is a critical component of airway management wherein the patient is made to breathe 100% oxygen to denitrogenate the functional residual capacity of lungs and create adequate oxygen reservoir. However, a tight seal required for ideal preoxygenation is not always possible due to factors such as emergency scenarios, facial traumas, patients with beard, uncooperative or edentulous patients or lack of specialized circuits. A nasal cannula is often used during apneic oxygenation and its addition to face mask while preoxygenation can improve its efficacy. Oxygen at a flow rate of 0 and 5 L/min has been found to be deleterious due to room air entrainment while a flow rate of 10 L/min has shown no impairment of preoxygenation process. Hence, we are conducting this study to compare and evaluate different oxygen flow rates supplied through a nasal cannula on the efficacy of preoxygenation.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients scheduled for elective surgery under anaesthesia.
Exclusion Criteria
- •Known lung disease Suspected coronary and cerebrovascular disease Previous exposure to bleomycin or amiodarone Pregnancy BMI>35 Pathological abdominal distention Factors affecting mask seal like beard, moustache, dentures or facial abnormalities.
Outcomes
Primary Outcomes
End tidal oxygen concentration after 3 mins of preoxygenation in well-sealed face mask and in a combination of both face mask and nasal cannula (at flow rates of 0L/min, 5L/min and 10L/min
Time Frame: 3 minute
Secondary Outcomes
- End tidal oxygen concentration after 1 and 2 mins of preoxygenation in well-sealed face mask and in a combination of both face mask and nasal cannula (at flow rates of 0L/min, 5L/min and 10L/min(1 minute)