Comparison of Emergency Department Preoxygenation Techniques in Healthy Volunteers
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiratory Failure
- Sponsor
- Hennepin Healthcare Research Institute
- Enrollment
- 26
- Primary Endpoint
- Exhaled Oxygen Concentration
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Four methods of preoxygenation will be compared in healthy volunteers
Detailed Description
After informed consent, each volunteer will undergo the following techniques: Simple mask at "flush" flow (40-60 L/min) Non-rebreather mask at 15 L/min Non-rebreather mask at 60 L/min Bag valve mask with one way exhalation valve at 15 L/min After 3 minutes, the exhaled oxygen will be measured with an oxygen sensor
Investigators
Brian Driver
Associate Research Director
Hennepin Healthcare Research Institute
Eligibility Criteria
Inclusion Criteria
- •Over 18 years old
Exclusion Criteria
- •Any active respiratory pathology (asthma, chronic obstructive pulmonary disease, other lung disease, smoking history more than 5 years)
Outcomes
Primary Outcomes
Exhaled Oxygen Concentration
Time Frame: Immediately after 3 minutes of oxygen supplementation
Subjects will blow into an oxygen sensor after each method (arm). The primary outcome will be a non-inferiority test between bag valve mask and non-rebreather at 60 L/min. The remaining tests will be completed for comparison, but not part of formal statistical testing.