A Comparison of Pre-oxygenation Techniques in Pregnant Patients Prior to a Cesarean Delivery - A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- End Tidal Oxygen Concentration (ETO2) Following Tidal Volume Breathing Using Either Face Mask or OptiFlow
研究概览
简要总结
A trial comparing outcomes of two pre-oxygenation techniques in obstetric patients.
详细描述
Pre-oxygenation is performed prior to general anesthesia to prevent hypoxia during airway management. It is typically performed using a standard tight-fitting face mask; however, recent advances in oxygenation have occurred through the use of trans-nasal oxygen delivery devices, such as OptiFlow. There is limited evidence of the use of OptiFlow in the pregnant patient, and as such, this study aims to show that OptiFlow is as effective at pre-oxygenation as a standard tight-fitting face-mask technique in the pregnant population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy (American Society of Anesthesiologists class 1 or 2), pregnant patients ≥36 weeks gestation scheduled for elective Cesarean delivery under neuraxial anesthesia.
排除标准
- •Comorbidities likely to alter outcome of respiration and gas exchange.
- •Patients only able to breathe through their mouth.
- •Patients who are in active labour.
- •Patients unable to tolerate a face mask being held over their mouth and nose.
- •Patients with a Body Mass Index ≥40kg/m
- •Patients who are unable to give informed consent.
结局指标
主要结局
End Tidal Oxygen Concentration (ETO2) Following Tidal Volume Breathing Using Either Face Mask or OptiFlow
时间窗: From baseline ETO2 concentration to the end of 3 minutes of tidal volume breathing
Concentration of oxygen at the end of a breath following 3 minutes of tidal volume breathing using either face mask or OptiFlow
次要结局
- End Tidal Oxygen Concentration (ETO2) Following Vital Capacity Breaths Using Either Face Mask or OptiFlow(From baseline ETO2 concentration to the end of 8 vital capacity breaths (approximately 3 minutes))
研究者
Anthony Chau
Clinical Assistant Professor
University of British Columbia