Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation in Al-Rajhy Liver Hospital in Upper Egypt.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Incidence of biliary complications
研究概览
简要总结
Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe .
a prospective study and retrospective part from hospital records.
Aim of the study:
- Detect frequency, risk factors for development of biliary complications post living donor liver transplantation, types (stricture anastomotic or not, leak, biloma, stone, cholangitis etc....).
- Evaluate outcomes of different biliary complications
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt
排除标准
- •pediatric liver transplantation
- •cadaveric liver transplantation
结局指标
主要结局
Incidence of biliary complications
时间窗: 1 year after liver transplantation
Biliary complications include biliary leak or stricture (anastomotic or non anastomotic), the investigator will record nature of complication , its time of presentation and number of hospital re-admissions due to biliary complications.
Type of intervention done to each complication
时间窗: 1 year after liver transplantation
Intervention is either non surgical (ERCP or PTD) or surgical revision with detailed description of each intervention and if the intervention is successful or not (biliary stricture resolved by MRCP, improvement of liver functions and symptoms)
次要结局
未报告次要终点
研究者
Sara Ali Hassan
Clinical teaching assistant in department of Tropical Medicine and Gastroenterology
Assiut University