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Clinical Trials/NCT04188717
NCT04188717
Completed
Not Applicable

Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation- A Retrospective Analysis

Institute of Liver and Biliary Sciences, India0 sites253 target enrollmentJanuary 1, 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Liver Transplant; Complications
Sponsor
Institute of Liver and Biliary Sciences, India
Enrollment
253
Primary Endpoint
Mortality
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.

Registry
clinicaltrials.gov
Start Date
January 1, 2010
End Date
January 1, 2017
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • patients undergoing liver transplant surgery
  • 18-65 years

Exclusion Criteria

  • pregnant patients
  • Acute Liver Failure, Acute on Chronic Liver Failure

Outcomes

Primary Outcomes

Mortality

Time Frame: 90 days

mortality due to any cause

Neurological complications

Time Frame: 90 days

type of neurological complication

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