Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation- A Retrospective Analysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Liver Transplant; Complications
- Sponsor
- Institute of Liver and Biliary Sciences, India
- Enrollment
- 253
- Primary Endpoint
- Mortality
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients undergoing liver transplant surgery
- •18-65 years
Exclusion Criteria
- •pregnant patients
- •Acute Liver Failure, Acute on Chronic Liver Failure
Outcomes
Primary Outcomes
Mortality
Time Frame: 90 days
mortality due to any cause
Neurological complications
Time Frame: 90 days
type of neurological complication