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临床试验/NCT04188717
NCT04188717已完成不适用

Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation- A Retrospective Analysis

Institute of Liver and Biliary Sciences, India0 个研究点目标入组 253 人开始时间: 2010年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
253
主要终点
Mortality

研究概览

简要总结

Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients undergoing liver transplant surgery
  • 18-65 years

排除标准

  • pregnant patients
  • Acute Liver Failure, Acute on Chronic Liver Failure

结局指标

主要结局

Mortality

时间窗: 90 days

mortality due to any cause

Neurological complications

时间窗: 90 days

type of neurological complication

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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