Changes in Body Composition and Nutritional Status Assessed by Bioelectrical Impedance Vector Analysis in Cirrhotic Patients Undergoing Liver Transplantation
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Body composition
Study Overview
Brief Summary
Liver transplant is the goal treatment for every patient with end-stage chronic liver disease.
Quality of life improves after transplant because the main complications of end-stage liver disease disappear, but due to immunosuppression other alterations appear such as metabolic alterations, weight gain, among others.
Body composition and nutritional status can be affected do to post-transplant pharmacologic therapy.
Detailed Description
Body composition and nutritional status can be affected due to post-transplant pharmacologic therapy.
This is a prospective cohort study, patients from liver transplant waiting list will be assessed, pre and post-transplant measures of body composition and nutritional status will be obtained.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Liver cirrhosis (any etiology)
- •Enrolled in waiting list for tliver transplant
Exclusion Criteria
- •Hepatocellular carcinoma
- •Chronic renal failure
- •Congestive cardiac failure
- •Extremity amputation
- •Pregnancy
Outcomes
Primary Outcomes
Body composition
Time Frame: Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant
Body composition will be assessed through bioelectrical impedance vector analysis graph.
Secondary Outcomes
- Liver function tests(Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant)
Investigators
ALDO TORRE DELGADILLO
Principal investigator
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran