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Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation

Conditions
Liver Transplant; Complications
Registration Number
NCT03789383
Lead Sponsor
Assiut University
Brief Summary

Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe .

a prospective study and retrospective part from hospital records.

Aim of the study:

1. Detect frequency, risk factors for development of biliary complications post living donor liver transplantation, types (stricture anastomotic or not, leak, biloma, stone, cholangitis etc....).

2. Evaluate outcomes of different biliary complications

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt
Exclusion Criteria
  • pediatric liver transplantation
  • cadaveric liver transplantation

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of biliary complications1 year after liver transplantation

Biliary complications include biliary leak or stricture (anastomotic or non anastomotic), the investigator will record nature of complication , its time of presentation and number of hospital re-admissions due to biliary complications.

Type of intervention done to each complication1 year after liver transplantation

Intervention is either non surgical (ERCP or PTD) or surgical revision with detailed description of each intervention and if the intervention is successful or not (biliary stricture resolved by MRCP, improvement of liver functions and symptoms)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Al-Rajhy liver hospital

🇪🇬

Assiut, Egypt

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