The Effectiveness of Preemptive Effect of Rectus Sheath Block and Intercostal Block on Postoperative Visceral Pain in Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Difference of analgesic consumption between both group
研究概览
简要总结
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
After induction of general anesthesia, group of patient is decided randomly. In Group pre, RSB and ICNB are performed with 0.25% Ropivacaine 40ml before the operation. In Group post, RSB and ICNB are performed with 0.25% Ropivacaine 40ml after the operation.
Measure the NRS and compare the rescue analgesic dose used at 0, 0.5, 1, 2, 6, 9, 18, and 24 hours after arrival at the recovery room.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adults between the ages of 20 and 80
- •scheduled laparoscopic cholecystectomy patient
- •ASA class 1 or 2
- •Patients who have voluntarily agreed in writing to participate in the trial
排除标准
- •Patient with side effects on local anesthetics or steroids
- •Patient who are taboo of peripheral nerve block such as blood clotting disorder, infection, etc.
- •Patients with uncontrolled medical or psychiatric problem
- •Patient does not agree to participate in the study
- •Patients who are pregnant or lactating
- •Patients whose visceral pain is expected to be too severe
- •Patients receiving a single laparoscopic cholecystectomy (including using a robot)
研究组 & 干预措施
preoperative Rectus sheath block: group Pre
ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml Before surgical incision
干预措施: Ultrasound guided Rectus sheath block (Drug)
preoperative Rectus sheath block: group Pre
ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml Before surgical incision
干预措施: Intercostal nerve block (Drug)
postoperative Rectus sheath block: group Post
ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml After surgical incision
干预措施: Ultrasound guided Rectus sheath block (Drug)
postoperative Rectus sheath block: group Post
ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml After surgical incision
干预措施: Intercostal nerve block (Drug)
结局指标
主要结局
Difference of analgesic consumption between both group
时间窗: at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation
The difference in analgesics usage between the two groups after the operation is checked at fixed intervals (at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation) to compare.
次要结局
- compare the Numeric rating scale (NRS)(at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation)
研究者
Jong Hyuk Lee
clinical assistant professor
Asan Medical Center