NCT02241564已完成不适用
Follow-up of Malignancies in Transplanted Patients
Uppsala University1 个研究点 分布在 1 个国家目标入组 95 人开始时间: 2007年11月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 95
- 试验地点
- 1
- 主要终点
- Patient survival
研究概览
简要总结
The aim of the project is to improve the overall treatment and outcome of renal, pancreas or liver transplanted patients who have encountered a malignancy by a structured treatment program for diagnosis and treatment of the malignancy, optimization of the immunosuppressive treatment, follow-up and evaluation of the program.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients willing and capable of giving written informed consent of participation in the project
- •Patients with a previous diagnosed or presently diagnosed or reoccurrence of a malignancy (other then basal cell carcinoma)
排除标准
- •Patients with a primary liver cancer as cause of the transplantation
研究组 & 干预措施
Malignancy post transplantation
干预措施: Referral to a multidisciplinary expert panel at the Uppsala University Hospital after tumor detection (Other)
Malignancy post transplantation
干预措施: Switch from calcineurin inhibitor to an mTOR inhibitor (Drug)
结局指标
主要结局
Patient survival
时间窗: 12 months, 2 years, 3 years
After inclusion
次要结局
- ImmuKnow Assay value(12 months)
- Graft survival(12 months, 2 years, 3 years)
- Tumour progression/regression/reoccurrence(12 months, 2 years, 3 years)
- Maintained switch of immunosuppression from calcineurin inhibitor to mTOR inhibitor(3 years)
- Kidney function(12 months, 2 years, 3 years)
研究者
Tomas Lorant
Associate professor
Uppsala University
研究点 (1)
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