Take home naloxone intervention in multicentre emergency settings
- Conditions
- Opioid overdoseInjury, Occupational Diseases, PoisoningOther opioids
- Registration Number
- ISRCTN13232859
- Lead Sponsor
- Swansea University
- Brief Summary
2019 Protocol article in http://dx.doi.org/10.1136/emermed-2019-999.24 protocol (added 01/08/2019) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39198758/ (added 02/09/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 200
Eligible for intervention:
Adult (18 years of age or over, male or female) opioid users at risk of overdose who are attended by emergency ambulance paramedic or who attend ED
Accompanying friends, relatives or carers (18 years of age or over, male or female) of opioid users at risk of overdose who are attended by emergency ambulance paramedic or who attend ED
Eligible for inclusion in outcome follow up and analyses:
High risk peers (18 years of age or over, male or female) - opioid users at high risk of fatal opioid overdose who make up a wider peer group who may or may not make contact with emergency services at study site during the study period
1. Under 18 years of age
2. Actively dissent from involvement in study
3. Non-opioid overdose
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality (total and opioid overdose related), collected using anonymised data linkage at a single time point 12 months post intervention
- Secondary Outcome Measures
Name Time Method Collected using anonymised data linkage at a single time point 12 months post intervention:<br>1. Emergency admissions<br>2. ITU admissions<br>3. ED attendances (total and opioid overdose related)<br>4. 999 attendances (total and opioid overdose related)<br>5. THN kits issued<br>6. NHS resource usage