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The comparison of effects of drug in thoracic surgery

Phase 2
Conditions
One-lung ventilation in thoracic surgery.
Other specified respiratory disorders
Registration Number
IRCT2015123013159N8
Lead Sponsor
Vice Chancellor for Research, Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
122
Inclusion Criteria

1) Aged 18-75 years; 2) sustaining ASA I and ASA II; and 3) consent to thoracic surgery according to OLV under investigation.
Exclusion criteria: 1) Liver failure; 2)ischemia or heart valve disease; 3) history of anesthesia; 4) obstructive pulmonary disease with limitation in end-stage; 5) patients with OLV less than 30 minutes; 6) patients whose breath count reached 12 at the onset of anesthesia and before one-lung ventilation; and 7) patients with HRCT, PFT, and pathological lesions in the left lung.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Evaluation of end-tidal carbon dioxide pressure. Timepoint: 10 and 20 minutes after intervention. Method of measurement: Capnography; mm Hg.
Secondary Outcome Measures
NameTimeMethod
Evaluation of arterial carbon dioxide pressure. Timepoint: 10 and 20 minutes after intervention. Method of measurement: Pulse oximetry; mm Hg.
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