Anatomical Study of the Arteries of the Skin on Amputation Legs

• Conditions: Arteritic Leg Ulcer

• Registration Number: NCT03618615
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

PRIMARY OBJECTIVE Qualitatively describe the distribution of cutaneous arteries in patients with long-term occlusive arterial disease.

SECONDARY OBJECTIVE To compare the distribution of cutaneous arteries observed on the legs of arteritic patients with that observed on non-arteritic legs (from bodies given to science).

Detailed Description

Arterial patient coming to CHRU Nancy, in the Vascular and Endoluminal Surgery Department, to undergo leg amputation.

Usually, after the amputation of the leg in the operating theatre, the surgical waste is destroyed.

Instead of being destroyed, the leg will be used for research.

Study Timeline

• Study First Submitted: 2018-08-01
• Study First Submitted QC: 2018-08-01
• Study First Posted: 2018-08-07
• Status Verified: 2018-09
• Last Update Submitted: 2018-09-11
• Last Update Posted: 2018-09-12
• Study Start: 2018-09-30
• Primary Completion: 2021-09-30
• Study Completion: 2021-09-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Major Patient
• Patient with late stage occlusive arteriopathy with lower limb amputation
• Patient who did not oppose the search
• Patient affiliated to a social security scheme

Exclusion Criteria

• Patients with infectious diseases not accessible in the anatomy laboratory
• Woman of childbearing age without effective contraception
• Persons referred to in Articles L. 1121-5 to L. 1121-8 and L1122-2 of the Public Health Code :
• Pregnant woman, parturient or nursing mother
• Person deprived of liberty by a judicial or administrative decision,
• Person under psychiatric care pursuant to Articles L.3212-1 and L.3213-1 of the Public Health Code
• Person admitted to a health or social institution for purposes other than research
• Minor person (not emancipated)
• Adult subject to a legal protection measure (guardianship, trusteeship, protection of justice)
• Major person who is not in a position to express consent and who is not subject to a legal protection measure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Qualitative mapping of the skin's arteries.	72 hours after the dissection of the leg.	The leg will be transported in a container to the Anatomy Laboratory (Faculty of Medicine - University of Lorraine).; Within 72 hours of its arrival, the operating room will be dissected to qualitatively describe the distribution of cutaneous arteries in patients with long-term occlusive arterial disease.