The impact of aerobic exercise pre-conditioning to maximize the skeletal muscle adaptive response to resistance type exercise training in healthy older adults

Completed

• Conditions: Sarcopenie; age-related loss of muscle mass; sarcopenia

• Registration Number: NL-OMON52892
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 36

Inclusion Criteria

- Aged between 65-85
- Healthy
- 18 * BMI * 30 kg/m2

Exclusion Criteria

- Smoking
- Diabetes
- Cardiovascular disease
- Participation in any structured training program

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Type II muscle fiber size (muscle biopsy)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Whole body- and regional body composition (DEXA and MRI scan), muscle strength<br /><br>and physical performance (1RM, SPPB, TUG, handgrip strength), muscle fiber<br /><br>characteristics (muscle biopsy), microvascular perfusion (CEUS) and oral<br /><br>glucose tolerance (OGTT) will be secondary parameters.</p><br>