The effect of endurance exercise training on muscle mass gains during subsequent resistance exercise training in older adults
Not yet recruiting
- Conditions
- Sarcopenia
- Registration Number
- NL-OMON22675
- Lead Sponsor
- Maastricht University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 72
Inclusion Criteria
•Age between 65 and 85 y
•BMI between 18.5 and 30 kg/m2
Exclusion Criteria
•HbA1C level above 6.5%
•Fasted blood glucose level above 6.9 mmol/L and/or 2 hour OGTT glucose level higher than 11.1 mmol/L
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •Type II muscle fiber size (muscle biopsy)
- Secondary Outcome Measures
Name Time Method •Muscle fiber vascularization (muscle biopsy)<br /><br>•Muscle microvascular perfusion (CEUS)<br /><br>•Whole-body skeletal muscle mass (MRI)<br /><br>•Whole-body and regional body lean tissue mass (DEXA)<br /><br>•Muscular strength (1 RM – each exercise machine)<br /><br>•Aerobic capacity (VO2peak cycling test)<br /><br>•Physical performance (short physical performance battery, timed up-and-go, handgrip strength)<br /><br>•Metabolic health (OGTT)<br /><br>•Acute muscle satellite cell response to a single bout of exercise (muscle biopsy)<br>