IRCT20150629022965N19
Completed
Phase 2
Evaluating the effects of oral N-acetyl cysteine as an adjuvant therapy for pain management and serum level of oxidative stress bio-markers in patients with painful diabetic neuropathy: a double-blind randomized clinical trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Diabetic polyneuropathy.
- Sponsor
- Hamedan University of Medical Sciences
- Enrollment
- 140
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age: 30 to 70 years old
- •History of type 2 diabetes at least one year ago
- •Hemoglobin A1c less than or equal to 10
- •Diabetic neuropathy with NDS score greater than or equal to 6, VAS scores for pain at least 4 and NSS score greater than or equal to 5
- •glomerular filtration rate more than 30
Exclusion Criteria
- •Type 1 diabetes
- •Pregnancy or breastfeeding
- •Diabetic foot ulcer
- •Neuropathy for reasons other than diabetes
- •History of cerebrovascular disease and discopathy
- •Use other medications to relieve symptoms of neuropathy
- •Use of alcoholic drinks or opioids
Outcomes
Primary Outcomes
Not specified
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