Short term Pretreatment with Atorvastatin for Reduction of early recurrence of Tachyarrhythmias after cather Ablation for Atrial Fibrillation (SPARTA-AF)

Not Applicable

Withdrawn

• Conditions: Diseases of the circulatory system

• Registration Number: KCT0000078
• Lead Sponsor: Koera University Guro Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1) Age >= 18
2) Subject with atrial fibrillation that is indicated to radiofrequency catheter ablation
3) Radiofrequency catheter ablation must be able to perform
4) Subject who able to take antiplatelet agent (aspirin, clopidogel), anticoagulant agent (warfarin) and antiarrhythmic agent for more than one year
5) Subject who give written consent to this study

Exclusion Criteria

1) Subject with intracardiac thrombus
2) Uncontrolled hypertension
3) Chronic kidney disease (serum creatinine > 2.0 mg/dl)
4) Chronic alcoholics, severe hepatosis (more than three-fold of upper normal range)
5) Subject who is taking prohibited combination drug with atorvastatin (intraconazole, ketoconazole etc.)
6) Chronic obstructive pulmonary disease
7) Significant valvular heart disease
8) History of coagulopathy
9) Chronic heart failure
10) Previous history of radiofrequency catheter ablation
11) Pregnancy
12) Hypersensitibity to contrast
13) Life expectancy under one year due to the other diseases

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recurrence rate of tachyarrhythmia

Secondary Outcome Measures

Name	Time	Method
Cardiovascular outcome;All cause mortality