Brain Metastasis Development Mechanism in BCBM Patients

Not Applicable

Recruiting

• Conditions: Breast Cancer; Brain Metastasis
• Interventions: Procedure: WGS/TME evaluation

• Registration Number: NCT06330870
• Lead Sponsor: Samsung Medical Center

Brief Summary

This study is the experimental study for brain metastasis development mechanism in patients with breast cancer with brain metastasis

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-06
• Study First Submitted: 2024-02-06
• Status Verified: 2024-03
• Study First Submitted QC: 2024-03-19
• Last Update Submitted: 2024-03-19
• Study First Posted: 2024-03-26
• Last Update Posted: 2024-03-26
• Primary Completion: 2025-02-05
• Study Completion: 2027-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Breast cancer
• Brain metastasis curative surgery patient

Exclusion Criteria

• Gamma Knife surgery patient

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
WGS/TME evaluation	WGS/TME evaluation	This is not intervention clinical trial design. We explore whole genome sequencing and tumor microenvironment evaluation for brain metastasis specimen in breast cancer patients.

Primary Outcome Measures

Name	Time	Method
Intracranial disease free survival	Months	Time to new brain metastasis or brain metastasis progression from the brain surgery

Trial Locations

Locations (1)

Ji-Yeon Kim; 🇰🇷 Seoul, Korea, Republic of