2022-501304-10-00招募中4 期
Bicarbonate for In-Hospital Cardiac Arrest – A Randomized, Double-Blind, Placebo-Controlled Trial
Aarhus University Hospital19 个研究点 分布在 1 个国家目标入组 778 人开始时间: 2022年9月26日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 778
- 试验地点
- 19
- 主要终点
- Return of spontaneous circulation
研究概览
简要总结
To determine whether sodium bicarbonate, as compared to placebo, when administered during in-hospital cardiac arrest, will increase return of spontaneous circulation.
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 接受健康志愿者
- 是
入选标准
- •In-hospital cardiac arrest
- •Age ≥ 18 years
- •Received at least one dose of adrenaline during cardiopulmonary resuscitation
排除标准
- •Clearly documented “do-not-resuscitate” order prior to the cardiac arrest
- •Prior enrollment in the trial
- •Invasive mechanical circulatory support at the time of the cardiac arrest
- •Known or suspected pregnancy at the time of the cardiac arrest
- •Known objection by the patient to participate in the trial
- •Clinical indication for bicarbonate administration
结局指标
主要结局
Return of spontaneous circulation
Return of spontaneous circulation
次要结局
- Survival at 30 days
- Survival at 30 days with a favorable neurological outcome (modified Rankin Scale score 0 - 3)
研究者
Lars W. Andersen
Scientific
Aarhus University Hospital
研究点 (19)
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