the effect of duloxetine on theanxiety and depression of patients with diabetic neuropathy

Phase 2

• Conditions: Condition 1: Effect of Duloxetine on the Mental State of Patients (Anxiety) with Diabetic Neuropathy. Condition 2: Effect of Duloxetine on the Mental State of Patients (Depression) with Diabetic Neuropathy.; Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy; E08.43

• Registration Number: IRCT20210725051977N2
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 2 May 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Age between 20 to 85
Diabetic patients with sensory diabetic neuropathy in organs with symptoms of anxiety or depression (ASA patients 1-3)

Exclusion Criteria

Lack of patient cooperation in proper drug use or response
Drug intolerance by the patient
Pregnant women

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination mental state (anxiety / depression) of patients with diabetic neuropathy based on Beck questionnaire. Timepoint: Determining the score of anxiety and depression at the beginning of the study (before the intervention) and 30 days after taking duloxetine. Method of measurement: Beck Anxiety and Depression Inventory questionnaire.

Secondary Outcome Measures

Name	Time	Method
Intensity of pain Fingers or toes based on VAS scale. Timepoint: Determining the score of anxiety and depression at the beginning of the study (before the intervention) and 30 days after taking Duloxetine. Method of measurement: Visual Analogue Scale.;Frequency of adverse drug complications (Duloxetine). Timepoint: 30 days after taking Duloxetine. Method of measurement: ?Check list including possible adverse drug reactions following Duloxetine.