Cryoprobe Transbronchial Lung Biospy in Patients With Mechanical Ventilation

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau3 sites in 1 country15 target enrollmentNovember 2013

ConditionsLung Diseases Interstitial Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Lung Diseases
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Enrollment: 15
Locations: 3
Primary Endpoint: Adverse events related to transbronchial lung biopsy (TBLB) with cryoprobe
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to evaluate the the diagnostic yield and safety of transbronchial lung biopsies (TBLB) with cryoprobe in patients with mechanical ventilation.

Registry

clinicaltrials.gov

Start Date

November 2013

End Date

December 2015

Last Updated

10 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•≥18 years old
•Patients with mechanical ventilation.
•Patients with diffuse lung disease of unknown etiology.
•Need for confirming/excluding a diagnosis, with therapeutical and prognosis implications.
•Inform consent signed by family.

Exclusion Criteria

•Use of anticoagulant therapy or presence of a coagulation disorder (abnormal platelets counts, international normalized ratio \> 1.5).
•Comorbidities that could increase the risk of the TBLB.
•Bullous emphysema.
•Hemoptysis, pneumothorax.
•Severe respiratory insufficiency requiring PEEP \>12 cm H2O