Application of Transbronchial Cryobiopsy in the Diagnosis of Progressive Pulmonary Fibrosis：a Multicenter Prospective Study

China-Japan Friendship Hospital1 site in 1 country100 target enrollmentFebruary 1, 2024

ConditionsPulmonary Fibrosis Transbronchial Cryobiopsy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Pulmonary Fibrosis
Sponsor: China-Japan Friendship Hospital
Enrollment: 100
Locations: 1
Primary Endpoint: the diagnostic performance of transbronchial cryobiopsy（TBLC）
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this clinical study is to learn about the diagnostic effectiveness, safety, and influencing factors of transbronchial cryobiopsy（TBLC）in progressive pulmonary fibrosis. The main question it aims to answer are: • Determine the prognosis, health economics, and therapeutic strategy changes of patients with TBLC retrograde malleable pulmonary fibrosis. Participants will be randomly divided into two groups, and received TBLB or TBLC.

Registry

clinicaltrials.gov

Start Date

February 1, 2024

End Date

December 31, 2026

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

China-Japan Friendship Hospital

Responsible Party

Principal Investigator

Gang Hou

Principal Investigator

China-Japan Friendship Hospital

Eligibility Criteria

Inclusion Criteria

•Patients with PPF, ≥18 years of age, unclassified ILD, HRCT ≤3 months, forced vital capacity (FVC)≥50% predicted value, pulmonary carbon monoxide diffusion (DLCO)≥35% predicted value, echocardiography ≤12 months, estimated pulmonary systolic blood pressure ≤40 mmHg, Body mass index (BMI)≤35 kg/m2.