Monocytosis and Culprit Vessel in STEMI Patients

Completed

• Conditions: STEMI

• Registration Number: NCT01569646
• Lead Sponsor: Northwell Health

Brief Summary

Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality. Now monocytes which are a subset of white blood cells may have a prognostic value for patients presenting with acute ST segment elevation myocardial infarction. A monocyte count of greater than 800/mm3 following acute myocardial infarction has been shown to be associated with increased incidence of left ventricular dysfunction. The investigators study would retrospectively collect data on patients with ST elevation myocardial infarction, looking for an association between high monocyte count and the culprit vessel causing the myocardial infarction. The investigators would also investigate whether monocytosis would be a marker of poor prognosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04
• Study First Submitted: 2010-06-02
• Status Verified: 2012-03
• Study First Submitted QC: 2012-03-30
• Last Update Submitted: 2012-03-30
• Study First Posted: 2012-04-03
• Last Update Posted: 2012-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 226

Inclusion Criteria

• STEMI

Exclusion Criteria

• Patients on antibiotics and steroids

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Association between monocyte count and culprit vessel	1 day

Secondary Outcome Measures

Name	Time	Method
clinical outcomes of troponin and monocyte in stemi patients	0 - 6 months

Trial Locations

Locations (1)

Staten Island University Hospital; 🇺🇸 Staten Island, New York, United States