Prognostic Value of Serum Cholesterol and Triglyceride in Septic and Non Septic Patients: Randomized Double Blinded Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- change in the level of serum cholesterol and triglyceride
研究概览
简要总结
The primary outcome of this study is to evaluate the difference between the level of serum cholesterol and triglyceride in septic and non septic patients in the ICU. .
The secondary outcome will be to find correlation between the level of serum cholesterol and triglyceride and both Acute physiology And Chronic Health Evaluation Score (APACHE) II(19) and quick Sequential Organ Failure Assessment (qSOFA) score (20) and their relation to mortality.
详细描述
Type and Site of The study:
This study will be be done at Beni-Suef university hospital SICU after approval of the local ethics and research committee and anesthesia department of Beni-Suef University.
DATE AND PERIOD OF THE STUDY:
The study will be done between June 2017 and June 2018
Study population:
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The study population will include the patients (age range between 20 and 70) of both sex (septic and non septic patients e.g. trauma patients, post surgical patients) who will be admitted to the surgical intensive care in Beni-Suef University hospital
排除标准
- •Age less than 20
- •Pregnancy
- •ICU readmission
- •Dyslipidemia
- •Patients with liver disease e.g.hepatitis B,hepatitis C , liver cirrhosis, and hepatocellular carcinoma)
- •Concomitant of use immunosuppressive therapy
- •Using statin or steroid (≥15mg/day) within the previous 7 days
- •Patients who had been treated with corticosteroid therapy for septic shock prior to admission to ICU
- •Patients sedated by propofol
结局指标
主要结局
change in the level of serum cholesterol and triglyceride
时间窗: on days 0, 1, 3, and 7, 10 and 14 days
change in the level of serum cholesterol and triglyceride
次要结局
未报告次要终点
研究者
doaa rashwan
assistant professor
Beni-Suef University