Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing

Terminated

• Conditions: Other Skin Disorders; Mycosis Fungoides; Cutaneous T-cell Lymphoma; Cutaneous Lymphoma

• Registration Number: NCT01556828
• Lead Sponsor: Stanford University

Brief Summary

The goal of this study is to identify genetic changes associated with the initiation, progression, and treatment response of response of cutaneous and hematologic disorders using recently developed high-throughput sequencing technologies. The improved understanding of the genetic changes associated with cutaneous and hematologic disorders may lead to improved diagnostic, prognostic and therapeutic options for these disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-06
• Study First Submitted: 2012-03-14
• Study First Submitted QC: 2012-03-15
• Study First Posted: 2012-03-16
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2016-06
• Last Update Submitted: 2016-06-22
• Last Update Posted: 2016-06-24

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• 18 years of age or older
• Patient meets the clinical and/or pathologic criteria for the cutaneous or hematologic disorder being examined.
• Patient is willing to provide skin biopsies and five 10 mL tubes of peripheral blood.

Exclusion Criteria

• Less than 18 years of age

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of mutations	2 years	Identify mutations, changes in DNA copy number, structural rearrangements, or altered coding and non-coding RNA expression

Trial Locations

Locations (1)

Stanford University, School of Medicine; 🇺🇸 Stanford, California, United States