Identification of Genetic Factors Determining Disease Course and Preparation of Pharmacogenetic Applications in the New Type of Coronavirus Infection, COVID-19
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19
- Sponsor
- Szeged University
- Enrollment
- 1000
- Locations
- 14
- Primary Endpoint
- Identification of genetic factors determining the course of the disease in case of COVID-19
- Last Updated
- 5 years ago
Overview
Brief Summary
The study aims to identify environmental factors and genetic (gene mutation and gene expression) changes, which influencing the course of the disease the new type of coronavirus infection COVID-19 in patients nationwide in a multicenter study.
At first in the study will be performed 200 patients, selected for a homogeneous groups on the basis of the patient's anamnestic data, genetic testing.
Following the interim analysis, based on the results, another 800 people are planned to involve.
Investigators
Eligibility Criteria
Inclusion Criteria
- •confirmed covid 19 infection
Exclusion Criteria
- •informed refusal
Outcomes
Primary Outcomes
Identification of genetic factors determining the course of the disease in case of COVID-19
Time Frame: 2020. December
Exploring genotype-phenotype connections based on anamnestic data of patients and joint bioinformatics analysis of its genetic variants